The Nigeria women's football team, the Super Falcons, and the Black Queens of Ghana will rekindle the fierce rivalry between them in Lagos on Wednesday as the race for qualification for the Women's Africa Cup of Nations begins across the continent.
Both the Falcons and Black Queens are seen as powerhouses as far as women football is concerned in Africa but one of them will miss the action at Morrocco 2022 with the newly-adopted qualification system by CAF.
Missing out on the AWCON is a costly option for both Nigeria and Ghana as it effectively means also automatically missing out on a chance to be at the World Cup.
With so much at stake, a potentially explosive tie is expected over two legs between these two West African neighbours.
Ghana and Nigeria have met in 17 previous matches, with the Super Falcons dominating with nine wins - compared to three victories registered by the Black Queens.
The Super Falcons will need more than their past records to navigate past the Ghanaian Ladies, and coach of the team, Randy Waldrum, admits his girls must get it right from Wednesday's first leg in Lagos.
Coach Waldrum said: "It is important for us to get a good win at home and then go to Accra and play like warriors. These are two battles that we must be ready for.
"The Super Falcons just have to be at the AFCON and the World Cup and they are ready to give these two matches their all."