Watch picture of the Black Stars departure to the Seville airport in Spain ahead of their departure to Equatorial Guinea for the Africa Cup of Nations finals.
The Black Stars camped in the European city for ten days and played two friendly matches against club sides.
Ghana beat Portuguese second-tier side Olhanense 3-1 in Portugal before coming from a goal down to draw 1-1 with Dutch Eredivise side SC Cambuur.
They will land in Equatorial Guinea at 23:25 GMT before checking in at their camp base in Mongomo.
Ghana's first match at the tournament will be against Senegal on 19 January before playing Algeria and South Africa.