Moroccan side, Pyramids FC, will be without key players Ramadan Sobhi, Osama Galal, and Mostafa Fathi for their CAF Champions League, Nigeriasoccernet.com report.
The matchday one clash with Rivers United is on Saturday.
The trio will miss the encounter at the 30 June Stadium in Cairo due to injury.
Head coach Krunoslav Jur?i? can, however, count on goalkeeper Ahmed El-Shenawy, Walid El Karti, and striker Fiston Mayele to lead the team.
Rivers United, making their maiden appearance in the group stage, will look to make a memorable start by getting a positive result against their hosts.
In the group's other tie, RS Berkane of Morocco will face Power Dynamos.
By Olujimi Dare Ogun