Enyimba attacking midfielder Ikechukwu Ibenegbu has eyed a double win over Kano Pillars at the Yakubu Gowon Stadium on Sunday.
Enyimba secured a 2-1 win over Pillars in the first half of the Nigeria Professional Football League (NPFL) campaign.
The defending champions are wary that their opponents will travel to Port Harcourt determined to avenge the first-round loss.
"We have heard and read as well that Kano Pillars are coming for avenge the first fixture loss in Kano, but we have told whoever that cares to listen that it will not be possible as far as we are concerned," Ibenegbu told SuperSport.
"Our minds are fixed and focused on making it a double against Pillars. We are strengthened for the daunting task by the Federation Cup round of 32 win against El Kanemi Warriors.
"However, we are not under any illusion that Kano Pillars will be easy to beat; Pillars are a good side and will go the extra-mile to prepare for the clash.
"So we are not going to take them for granted. But in saying that we are ready whatever antics and banter they will come up with to ensure we claim the three points at stake."
Enyimba are fifth in the table on 37 points, while Pillars are fourth on 39 points.