Serbia had the ball in the back of the net in the first half when Aleksandar Mitrovic headed home a poorly defended ball inside the Super Eagles box, but the goal was incorrectly ruled out for offside.
Super Eagles of Nigeria failed to create any meaningful chance in the first half which ended 0-0, but seven minutes after the hour mark Serbia took the lead.
Mitovic was left unmarked inside the Nigerian box and the striker who is on loan to Fulham from Newcastle United stroke home a well delivered cross from Dusan Tadic to put Serbia ahead.
Ten minutes before the end of the game, Mitrovic was once again left unmarked in the box, and from yet again another cross, the big man grabbed his brace of the tie to put his team two goals up.
Nigeria failed to mount any sufficient challenge to alter the score line as Serbia hanged on to clinch a well deserved 2-0 win over the Super Eagles of Nigeria